|
TMPY-03290
|
HGF Protein, Mouse, Recombinant
hepatocyte growth factor (hepapoietin A,NK1
|
Mouse
|
HEK293 Cells
|
|
HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1. |
|
TMPY-01905
|
CD160 Protein, Human, Recombinant (His)
BY55,NK1,NK28,CD160 mole...
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Human
|
HEK293 Cells
|
|
CD160 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.4 kDa and the accession number is O95971-1. |
|
TMPK-00059
|
CD94 Protein, Human, Recombinant (His & Avi), Biotinylated
NK cell receptor,CD94,KP43,KLRD1
|
Human
|
HEK293 Cells
|
|
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 19.8 kDa and the accession number is Q13241-1. |
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TMPY-05291
|
CD57/B3gat1 Protein, Human, Recombinant (mFc)
LEU7,NK1,beta-1,3-glucuronyltrans...
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Human
|
HEK293 Cells
|
|
B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. Saturating concentrations of rVAR2 inhibited downstream integrin signaling, which was mimicked by knockdown of the core chondroitin sulfate synthesis enzymes β-1,3-glucuronyltransferase 1 (B3GAT1) and chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1). |
|
TMPJ-00220
|
B3GAT1 Protein, Human, Recombinant (His)
beta-1,3-glucuronyltransferase 1 (glucuron...
|
Human
|
HEK293 Cells
|
|
B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. It adds a glucuronic residue to the terminal lactosamine residue (Gal beta 14GlcNAc) of a glycoprotein or glycolipid, which can be further sulfated to become the HNK1 epitope, a unique trisaccharide structure, HSO3-3GlcA beta 1-3Gal beta 1-4GlcNAc. The enzyme activity was found to be enhanced in the presence of sphingomyelin an... |
|
TMPK-00062
|
CD160 Protein, Human, Recombinant (His & Avi)
BY55FLJ46513,NK28,NK1, B...
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Human
|
HEK293 Cells
|
|
CD160 (also Natural killer cell receptor BY55) is a 27 ‑ 30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic cells. CD160 antigenis a receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta... |
|
TMPK-00058
|
CD94 Protein, Human, Recombinant (His & Avi)
KLRD1,KP43,NK cell receptor,CD94
|
Human
|
HEK293 Cells
|
|
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 19.8 kDa and the accession number is Q13241-1. |
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TMPJ-00567
|
NCR1 Protein, Human, Recombinant (hFc)
hNKp46,Natural cytotoxicity triggering receptor
|
Human
|
HEK293 Cells
|
|
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is a natural killer (NK) lymphocyte-activating receptor. It is involved in major aspects of NK immune function and shows a high degree of lineage specificity in blood and bone marrow. |
|
TMPY-03237
|
HGF Protein, Mouse, Recombinant (His)
SF/HGF,hepatocyte growth factor (hepapoietin A,肝细胞生长因子,N...
|
Mouse
|
HEK293 Cells
|
|
HGF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80.8 kDa and the accession number is Q08048-1. |
|
TMPK-01230
|
CLEC2D Protein, Human, Recombinant (hFc & Avi)
Lectin-like NK cell receptor,LLT-1,OCIL,LL...
|
Human
|
HEK293 Cells
|
|
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies. However, this implication may be confounded by highly active anti-retroviral treatment (HAART). |
|
TMPJ-00122
|
NKG2D/CD314 Protein, Mouse, Recombinant (His)
KLR,NKG2-D type II integral membrane protein,CD3
|
Mouse
|
HEK293 Cells
|
|
NKG2D/CD314 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is O54709. |
|
TMPJ-00097
|
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)
member 1,NK cell receptor D,NKG2-...
|
Cynomolgus
|
HEK293 Cells
|
|
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-Fc tag. The predicted molecular weight is 50-70 KDa and the accession number is P61252. |
|
TMPJ-00425
|
NCR1 Protein, Mouse, Recombinant (hFc)
NKp46,mNKp46,NK-p46,mAR-1
|
Mouse
|
HEK293 Cells
|
|
Natural cytotoxicity triggering receptor 1(NKp46/NCR1) is a single-pass type I membrane protein. It consists of two extracellular Ig-like domains followed by a short stalk region, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmictail. NKp46 is predominantly expressed in the embryo. It has a positive charge in its transmembrane domain that permits association with the ITAM-bearing signal adapter proteins, CD3 zeta and Fc epsilon RI gamma. These rec... |
|
TMPY-02381
|
NK1.1/KLRB1F Protein, Mouse, Recombinant (hFc)
Nkrp1f,MGC130066,MGC1300...
|
Mouse
|
HEK293 Cells
|
|
NK1.1/KLRB1F Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46 kDa and the accession number is Q8VD98. |
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TMPK-00159
|
IL-15RA Protein, Human, Recombinant (His & Avi)
IL-15 R α,IL-15RA/IL-15 R α/CD2
|
Human
|
HEK293 Cells
|
|
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development. IL-15RA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.3 kDa and the accession number is Q13261-1. |
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TMPK-00160
|
IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated
MGC104179,IL-15 R α,IL-1...
|
Human
|
HEK293 Cells
|
|
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development. IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.3 kDa and the accession number is Q13261-1. |
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TMPK-00746
|
NKp46/NCR1 Protein, Human, Recombinant (hFc)
CD335,NKP46FLJ99094,MAR-1,NCR1,
|
Human
|
HEK293 Cells
|
|
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 53.2 kDa and the accession numb... |
|
TMPK-00747
|
NKp46/NCR1 Protein, Human, Recombinant (mFc)
NKp46,NKP46FLJ99094,CD335,NCR1,MA...
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Human
|
HEK293 Cells
|
|
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 52.9 kDa and the accession numb... |
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TMPK-00956
|
CD161 Protein, Human, Recombinant (His)
KLRB1,NKRP1ANKR,CD1<...
|
Human
|
HEK293 Cells
|
|
CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment. CD161 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 19.6 kDa and the accession number is Q12918-1. |
|
TMPK-00955
|
CD161 Protein, Human, Recombinant (His & Avi), Biotinylated
NKRP1,HNKR-P1a,NK
|
Human
|
HEK293 Cells
|
|
CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment. CD161 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.4 kDa and the accession number is Q12918-1. |
|
TMPK-00117
|
NKG2A/CD159a Protein, Human, Recombinant (His & Avi)
KLRC1,NKG2A,NKG2-A,KLRD1...
|
Human
|
HEK293 Cells
|
|
NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. NKG2A marks a unique immune effector subset preferentially co-expressing the tissue-resident CD103 molecule, but not immune checkpoint inhibitors.It is expressed only in NK-cells, but not in T-cells or B-cells. NKG2A/CD159a Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.3 kDa and the accession number is P26715-1. |
|
TMPY-04040
|
CLEC2D Protein, Rat, Recombinant (hFc)
C-type lectin domain family 2, member D
|
Rat
|
HEK293 Cells
|
|
Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were detected primarily in hematopoietic cell lines and were found to be co-induced by the same activation signals. Although very low amounts of putative soluble CLEC2D protein isoforms could be produced by transfectants, CLEC2D isoforms 2 and 4 were efficiently expressed. CLEC2D uses g... |
|
TMPK-00118
|
NKG2A/CD159a Protein, Human, Recombinant (His & Avi), Biotinylated
CD159A,KLRD1,NKG2A,KLRC1...
|
Human
|
HEK293 Cells
|
|
NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. NKG2A marks a unique immune effector subset preferentially co-expressing the tissue-resident CD103 molecule, but not immune checkpoint inhibitors.It is expressed only in NK-cells, but not in T-cells or B-cells. NKG2A/CD159a Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.3 kDa and the accession number ... |
|
TMPK-00971
|
CRTAM Protein, Mouse, Recombinant (His)
CRTAM,CD355,CD355 antigen
|
Mouse
|
HEK293 Cells
|
|
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. CRTAM Pr... |
|
TMPK-00134
|
ULBP-1 Protein, Human, Recombinant (His & Avi)
ALCAN-beta,ALCAN-β,ULBP-1,MULT-1,NK
|
Human
|
HEK293 Cells
|
|
Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natural killer (NK) cells. ULBP-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9BZM6. |
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TMPK-00887
|
KIR3DL2 Protein, Human, Recombinant (His & Avi)
KIR3DL2,p140,NKAT4,NKAT4A,NK<...
|
Human
|
HEK293 Cells
|
|
KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linked homodimer. Each chain is composed of three immunoglobulin-like domains and a long cytoplasmic tail containing two immunoreceptor tyrosine-based inhibitory motifs. KIR3DL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The pred... |
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TMPK-00135
|
ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated
ALCAN-β,NKG2D ligand 1,ULBP-1,
|
Human
|
HEK293 Cells
|
|
Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natural killer (NK) cells. ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9BZM6. |
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TMPK-00177
|
LAIR1 Protein, Human, Recombinant (His & Avi)
CD305,LAIR1,LAIR-1,HLAIR1
|
Human
|
HEK293 Cells
|
|
LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium ... |
|
TMPK-00721
|
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
Neurotactin,CXC3C,ABCD-3,Fkn,Fractalkine,NTT,Cx3cl1...
|
Mouse
|
HEK293 Cells
|
|
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma. |
|
TMPJ-00187
|
CD300A Protein, Human, Recombinant (hFc & His)
CMRF35-like molecule 8,NK inhibitory receptor,CMRF-...
|
Human
|
HEK293 Cells
|
|
CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granu... |
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TMPJ-01432
|
CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated
mucin 16, cell surface associated,CA-125,C...
|
Human
|
HEK293 Cells
|
|
MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. MUC16 is over-expressed by tumor cells including ovarian and mesothelial cancers. The transmembrane form can adhere to mesothelin in the peritoneum, facilitating metastasis of ovarian cancer to the peritoneal cavity. MUC16 also binds galectin-1 on immune cells and enhances its expression on tumor cells. MUC... |
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TMPK-01165
|
MCEMP1 Protein, Mouse, Recombinant (hFc)
MGC132456,C19orf59,MCEMP1
|
Mouse
|
HEK293 Cells
|
|
A cecal ligation and puncture-induced sepsis mouse model was established to determine the expression of mast cell expression membrane protein 1 (MCEMP1). MCEMP1 in T lymphocytes isolated from sepsis mice were up- or downregulated by exogenous transfection in an attempt to investigate their effects on the release of inflammatory factors, the expression of immunoglobulins, the activity of T cell subsets and natural killer (NK) cells, as well as T lymphocyte apoptosis. |
|
TMPJ-00120
|
NKp80/KLRF1 Protein, Human, Recombinant (His)
Lectin-like receptor F1,C-type lectin domain family...
|
Human
|
HEK293 Cells
|
|
Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a 21 aa transmembrane region, and a 172 aa extracellular domain (ECD). The protein strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Its' function i... |
|
TMPJ-00131
|
NKG2DL Protein, Human, Recombinant (hFc)
ALCAN-β,NKG2DL1,UL16-binding prot...
|
Human
|
HEK293 Cells
|
|
NKG2D ligand 1, also called ULBP1, is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family. Unlike the classical MHC class I molecules and the MIC molecules possess α1, α2 and α3 domains, ULBP/RAET1 family members lack α3 domain. ULBP1 is recognized by the activating receptor NKG2D on the surface of cytotoxic natural killer (NK) and T cells, and then promotes the lysis of cells expressing ULBP1 which is important for the im... |
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TMPJ-00898
|
CD72 Protein, Human, Recombinant (Trx & His)
Lyb-2,B-Cell Differentiation Antigen CD72,CD72
|
Human
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E. coli
|
|
B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulat... |
|
TMPJ-00281
|
CADM1 Protein, Mouse, Recombinant (hFc)
IgSF4,NECL-2,Nectin-like protein 2,Immunoglobulin superfamil...
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Mouse
|
HEK293 Cells
|
|
Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. CADM1 acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in... |
|
TMPJ-00020
|
IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated
白介素,Eosinophil differentiation factor,B-cell differentiation...
|
Human
|
HEK293 Cells
|
|
IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functi... |
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TMPJ-01337
|
IL-21R Protein, Mouse, Recombinant (aa 20-236, His)
Nilr,IL-21R,Interleukin-21 receptor,IL-2
|
Mouse
|
HEK293 Cells
|
|
Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells, and keratinocytes. Both IL-21 and IL-4 are necessary for efficient B cell IgG1 production and normal germinal center architecture. B cell IL-21 R engagement i... |
|
TMPJ-00363
|
IL-12RB1 Protein, Human, Recombinant (hFc)
IL-12R-β1,IL-12R-BETA1,I...
|
Human
|
HEK293 Cells
|
|
Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL... |
|
TMPK-01385
|
CRTAM Protein, Canine, Recombinant (His)
CRTAM,CD355 antigen,CD355
|
Canine
|
HEK293 Cells
|
|
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. CRTAM Pr... |
|
TMPJ-00070
|
IL-18 Protein, Human, Recombinant (His)
GIF,IL-1 γ,白细胞介素,Iboctadekin,Interleukin-1...
|
Human
|
HEK293 Cells
|
|
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After... |
|
TMPJ-00264
|
LAMP1 Protein, Human, Recombinant (hFc)
LAMP-1,CD107a,Lysosome-Associated Membrane...
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Human
|
HEK293 Cells
|
|
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal sto... |
|
TMPY-02712
|
Serpin B3 Protein, Human, Recombinant (His)
T4-A,HsT1196,serpin peptidase inhibitor, c...
|
Human
|
Baculovirus Insect Cells
|
|
SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be... |
|
TMPJ-00831
|
CCL3 Protein, Mouse, Recombinant (His)
LD78 α,MIP-1 α,MIP1-a,MIP-1 alpha...
|
Mouse
|
E. coli
|
|
C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. Mature mouse CCL3 shares 73%, 91%, and 82% amino acid sequence identity with human, rat, and cotton rat CCL3, respectively. CCL3 exerts its biological functions through interactions with CCR1, CCR3, and CCR5. It is cleared from the extra... |
|
TMPJ-00323
|
Nectin-2 Protein, Mouse, Recombinant (hFc)
Herpes Virus Entry Mediator B,PVRL2,Poliovirus Receptor-Rela...
|
Mouse
|
HEK293 Cells
|
|
CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to mediate nectin binding to its ligands. Nectin2 is known to bind the pseudorabies virus, and herpes simplex virus2 (HSV2), involving in cell to cell spreading of these viruses. It does not bind poliovirus. As a homophilic adhesion molecule, CD112 is found concentrated in adherens ju... |
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TMPJ-01056
|
IL-18 Protein, Mouse, Recombinant (His)
Interferon γ-inducing factor,Interleukin-1 gamma,Ig...
|
Mouse
|
E. coli
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Interleukin-18 (IL-18）is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins... |
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TMPJ-01212
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ULBP-1 Protein, Mouse, Recombinant (His)
RAET1I,ULBP1,NKG2DL1
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Mouse
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HEK293 Cells
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Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or inte... |
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TMPY-04451
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AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
AMPK, AMPK(α1, β1, γ1)
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Human
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Baculovirus Insect Cells
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AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1. |
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TMPY-02501
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CD3D & CD3E Heterodimer Protein, Human, Recombinant
CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...
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Human
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HEK293 Cells
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CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. |
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TMPY-03878
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Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...
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Human
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HEK293 Cells
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Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. |
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